Catalysis

Catalysts are used in the production of a large variety of chemicals and fuels, as demonstrated by the fact that catalyst-based manufacturing accounts for about 60% of chemical products and 90% of processes (Senkan 2001). These numbers will likely increase in the future, con sidering all the advantages of a catalytic process: it requires only small amount of a ‘smart’ molecule to produce a large quantity of the desired compound; the catalyst usually allows operation under mild reaction conditions; also the economic benefits of an efficient catalytic process are enormous since it is less capital-intensive, has lower operating costs, produces products of higher purity and fewer by-products. In addition, catalysts provide important environmental benefits.

Due to economic and ecological factors, catalytic processes in the pro duction of fine chemicals are gaining in importance, especially in the area of asymmetric catalysis (Collins et al. 1997; Breuer et al. 2004). Accordingly, the practicing chemist has three major options: transition metal catalysts (Jacobsen et al. 1999), organocatalysts (Berkessel and Gröger 2004) or enzymes (Drauz and Waldmann 2002; Liese et al. 2006). All of them have advantages and disadvantages, which means that a given type of catalysis cannot be expected to provide general so lutions to all problems of relevance in academic and industrial labora tories. Therefore, research in all three approaches needs to be intensified.