Human Biology - Principles of Health and Disease

Biology is the natural science that involves the study of life and living organisms, including their physical structure, chemical composition, function, development and evolution. Modern biology is a vast field, composed of many branches. Despite the broad scope and the complexity of the science, there are certain unifying concepts that consolidate it into a single, coherent field. Biology recognizes the cell as the basic unit of life, genes as the basic unit of heredity, and evolution as the engine that propels the creation of new species. Living organisms are open systems that survive by transforming energy and decreasing their local entropy to maintain a stable and vital condition defined as homeostasis. See glossary of biology.

A disease is any condition which results in the disorder of a structure or function in a living organism that is not due to any external injury. The study of disease is called pathology, which includes the study of cause. Disease is often construed as a medical condition associated with specific symptoms and signs. It may be caused by external factors such as pathogens or by internal dysfunctions, particularly of the immune system, such as an immunodeficiency, or by a hypersensitivity, including allergies and autoimmunity.

Health is the ability of a biological system to acquire, convert, allocate, distribute, and utilize energy with maximum efficiency. The World Health Organization (WHO) defined human health in a broader sense in its 1948 constitution as "a state of complete physical, mental and social well-being and not merely the absence of disease or infirmity." This definition has been subject to controversy, in particular as lacking operational value, the ambiguity in developing cohesive health strategies and because of the problem created by use of the word "complete", which makes it practically impossible to achieve. Other definitions have been proposed, among which a recent definition that correlates health and personal satisfaction.

Humans (taxonomically Homo sapiens) are the only extant members of the subtribe Hominina. The Hominina are sister of the Chimpanzees with which they form the Hominini belonging to the family of great apes. They are characterized by erect posture and bipedal locomotion; high manual dexterity and heavy tool use compared to other animals; open-ended and complex language use compared to other animal communications; and a general trend toward larger, more complex brains and societies.

Human biology is an interdisciplinary area of study that examines humans through the influences and interplay of many diverse fields such as genetics, evolution, physiology, anatomy, epidemiology, anthropology, ecology, nutrition, population genetics and sociocultural influences. It is closely related to biological anthropology and other biological fields.