Knowledge Integration in Mechanical Production

The emergence of a unified cognitive moment relies on the coordination of scattered mosaics of functionally specialized brain regions. Here we review the mechanisms of large-scale integration that counterbalance the distributed anatomical and functional organization of brain activity to enable the emergence of coherent behaviour and cognition.

They never open their mouths without subtracting from the sum of human knowledge.

Part of the goods which are annually produced, and which are called wealth, is, strictly speaking, waste, because it consists of articles which ... either should not have been produced until other articles had already been produced in sufficient abundance, or should not have been produced at all. And some part of the population is employed in making goods which no man can make with happiness, or indeed without loss of self-respect, because he knows that they had much better not be made; and that his life is wasted in making them.